研究業績

2022

Structural basis for the oligomerization-mediated regulation of NLRP3 inflammasome activation
Ohto U, Kamitsukasa Y, Ishida H, Zhang Z, Murakami K, Hirama C, Maekawa S, Shimizu T
Proc Natl Acad Sci, USA 119, e2121353119

The structure of NLRP9 reveals a unique C-terminal region with putative regulatory function
Kamitsukasa Y, Nakano K, Murakami K, Hirata K, Yamamoto M, Shimizu T, Ohto U.
FEBS letters 596, 876-885

Structure of the bile acid transporter and HBV receptor NTCP
Asami, J., Terakado Kimura, K., Fujita-Fujiharu, Y., Ishida, H., Zhang, Z., Nomura, Y., Liu, K., Uemura, T., Sato, Y., Ono, M., Yamamoto, M., Noda, T., Shigematsu, H., Drew, D., Iwata, S., Shimizu, T., Nomura, N., Ohto, U
Nature 606, 1021-1026

Structure of SARS-CoV-2 membrane protein essential for virus assembly
Zhikuan Zhang, Norimichi Nomura, Yukiko Muramoto, Toru Ekimoto, Tomoko Uemura, Kehong Liu, Moeko Yui, Nozomu Kono, Junken Aoki, Mitsunori Ikeguchi, Takeshi Noda, So Iwata, Umeharu Ohto & Toshiyuki Shimizu 
Nature communications, 13, 4399

Discovery of a lectin domain that regulates enzyme activity in mouse N-acetylglucosaminyltransferase-IVa (MGAT4A)
Masamichi Nagae, Tetsuya Hirata, Hiroaki Tateno, Sushil K. Mishra, Noriyoshi Manabe, Naoko Osada, Yuko Tokoro, Yoshiki Yamaguchi, Robert J. Doerksen, Toshiyuki Shimizu & Yasuhiko Kizuka
Communications Biology, 5, 695